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Apoptosis induction by doxazosin and other quinazoline α(1)-adrenoceptor antagonists: a new mechanism for cancer treatment?
Doxazosin and related, quinazoline-based α(1)-adrenoceptor antagonists can induce apoptosis in prostate and various other normal, benign, smooth muscle, endothelial and malignant cells. Such apoptosis-inducing effects occur independently of α(1)-adrenoceptor antagonism and typically require much hig...
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| Veröffentlicht in: | Naunyn Schmiedebergs Arch Pharmacol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5451152/ https://ncbi.nlm.nih.gov/pubmed/19904527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-009-0462-4 |
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