Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes

AIMS/HYPOTHESIS: Identification of novel biomarkers for type 2 diabetes and their genetic determinants could lead to improved understanding of causal pathways and improve risk prediction. Methods In this study, we used data from non-targeted metabolomics performed using liquid chromatography coupled...

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Veröffentlicht in:Diabetologia
Hauptverfasser: Fall, Tove, Salihovic, Samira, Brandmaier, Stefan, Nowak, Christoph, Ganna, Andrea, Gustafsson, Stefan, Broeckling, Corey D., Prenni, Jessica E., Kastenmüller, Gabi, Peters, Annette, Magnusson, Patrik K., Wang-Sattler, Rui, Giedraitis, Vilmantas, Berne, Christian, Gieger, Christian, Pedersen, Nancy L., Ingelsson, Erik, Lind, Lars
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451119/
https://ncbi.nlm.nih.gov/pubmed/27406814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-4041-1
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