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Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy

Sample preparation is critical to biological electron microscopy (EM), and there have been continuous efforts on optimizing the procedures to best preserve structures of interest in the sample. However, a quantitative characterization of the morphological changes associated with each step in EM samp...

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Veröffentlicht in:PLoS One
Hauptverfasser: Zhang, Ying, Huang, Tao, Jorgens, Danielle M., Nickerson, Andrew, Lin, Li-Jung, Pelz, Joshua, Gray, Joe W., López, Claudia S., Nan, Xiaolin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451012/
https://ncbi.nlm.nih.gov/pubmed/28562683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176839
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