Matrix Metalloproteinase-19 Is a Key Regulator of Lung Fibrosis in Mice and Humans

Rationale: Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by epithelial phenotypic changes and fibroblast activation. Based on the temporal heterogeneity of IPF, we hypothesized that hyperplastic alveolar epithelial cells regulate the fibrotic response. Objectives: To ide...

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Publicado no:Am J Respir Crit Care Med
Main Authors: Yu, Guoying, Kovkarova-Naumovski, Elisabetha, Jara, Paul, Parwani, Anil, Kass, Daniel, Ruiz, Victor, Lopez-Otín, Carlos, Rosas, Ivan O., Gibson, Kevin F., Cabrera, Sandra, Ramírez, Remedios, Yousem, Samuel A., Richards, Thomas J., Chensny, Lara J., Selman, Moisés, Kaminski, Naftali, Pardo, Annie
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450991/
https://ncbi.nlm.nih.gov/pubmed/22859522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201202-0302OC
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