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Association of CYP17A1 Genetic Polymorphisms and Susceptibility to Essential Hypertension in the Southwest Han Chinese Population

BACKGROUND: The CYP17A1 gene encodes for cytochrome P450 enzyme CYP17A1, which is involved with the steroidogenic pathway including mineralocorticoids. The CYP17A1 polymorphisms might affect enzyme activity, then leading to a state of mineralocorticoid 11-deoxycorticosterone excess characterized by...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Li, Qian, Gao, Tangxin, Yuan, Yuncang, Wu, Yanrui, Huang, Qionglin, Xie, Fei, Ran, Pengzhan, Sun, Lijuan, Xiao, Chunjie
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450854/
https://ncbi.nlm.nih.gov/pubmed/28537227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.902109
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