Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7 prevents chromosome segregation and cytokinesis defects in oocytes

In most species, oocytes lack centrosomes. Accurate meiotic spindle assembly and chromosome segregation – essential to prevent miscarriage or developmental defects – thus occur through atypical mechanisms that are not well characterized. Using quantitative in vitro and in vivo functional assays in t...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Gigant, Emmanuelle, Stefanutti, Marine, Laband, Kimberley, Gluszek-Kustusz, Agata, Edwards, Frances, Lacroix, Benjamin, Maton, Gilliane, Canman, Julie C., Welburn, Julie P. I., Dumont, Julien
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450848/
https://ncbi.nlm.nih.gov/pubmed/28289130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.147504
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