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Increasing efficiency for estimating treatment-biomarker interactions with historical data

Detecting a treatment-biomarker interaction, which is a task better suited for large sample sizes, in a phase II trial, which has a small sample size, is challenging. In this paper, we investigate how two plausibly-available sources of historical data may contain partial information to help estimate...

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Bibliographic Details
Published in:Stat Methods Med Res
Main Authors: Boonstra, Philip S., Taylor, Jeremy M. G., Mukherjee, Bhramar
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450810/
https://ncbi.nlm.nih.gov/pubmed/24855118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280214535370
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