Physical mapping of human chromosomes by repetitive sequence fingerprinting.
We have developed an approach for identifying overlapping cosmid clones by exploiting the high density of repetitive sequences in complex genomes. Individual clones are fingerprinted, using a combination of restriction enzyme digestions followed by hybridization with selected classes of repetitive s...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1990
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2385591/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.16.6218 |
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