Identification and characterization of a cyclosporin binding cyclophilin from Staphylococcus aureus Newman

Cyclophilins, a class of peptidyl-prolyl cis-trans isomerase (PPIase) enzymes, are inhibited by cyclosporin A (CsA), an immunosuppressive drug. Staphylococcus aureus Newman, a pathogenic bacterium, carries a gene for encoding a putative cyclophilin (SaCyp). SaCyp shows significant homology with othe...

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Bibliografski detalji
Izdano u:Bioinformation
Glavni autori: Polley, Soumitra, Seal, Soham, Mahapa, Avisek, Jana, Biswanath, Biswas, Anindya, Mandal, Sukhendu, Sinha, Debabrata, Sau, Keya, Sau, Subrata
Format: Artigo
Jezik:Inglês
Izdano: Biomedical Informatics 2017
Teme:
Hypothesis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450249/
https://ncbi.nlm.nih.gov/pubmed/28584448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630013078
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