LPS promotes resistance to TRAIL-induced apoptosis in pancreatic cancer

BACKGROUND: Though TRAIL has been hailed as a promising drug for tumour treatment, it has been observed that many tumour cells have developed escape mechanisms against TRAIL-induced apoptosis. As a receptor of LPS, TLR 4, which is expressed on a variety of cancer cells, can be associated with TRAIL-...

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Veröffentlicht in:Infect Agent Cancer
Hauptverfasser: Beyer, Katharina, Partecke, Lars Ivo, Roetz, Felicitas, Fluhr, Herbert, Weiss, Frank Ulrich, Heidecke, Claus-Dieter, von Bernstorff, Wolfram
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450120/
https://ncbi.nlm.nih.gov/pubmed/28572836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13027-017-0139-4
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