Prognostic significance of LINE-1 hypomethylation in oropharyngeal squamous cell carcinoma

BACKGROUND: Inclusion of new biomarkers to improve a personalized treatment approach for oropharyngeal squamous cell carcinoma (OPSCC) is urgently needed. Hypomethylation of the Long interspersed nucleotide element-1 (LINE-1) repetitive elements, a widely accepted surrogate of overall genomic DNA me...

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Detalles Bibliográficos
Publicado en:Clin Epigenetics
Autores principales: Furlan, Carlo, Polesel, Jerry, Barzan, Luigi, Franchin, Giovanni, Sulfaro, Sandro, Romeo, Salvatore, Colizzi, Francesca, Rizzo, Aurora, Baggio, Vittorio, Giacomarra, Vittorio, Dei Tos, Angelo Paolo, Boscolo-Rizzo, Paolo, Vaccher, Emanuela, Dolcetti, Riccardo, Sigalotti, Luca, Fratta, Elisabetta
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450111/
https://ncbi.nlm.nih.gov/pubmed/28572862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0357-z
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