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Uracil DNA glycosylase (UDG) activities in Bradyrhizobium diazoefficiens: characterization of a new class of UDG with broad substrate specificity

Repair of uracils in DNA is initiated by uracil DNA glycosylases (UDGs). Family 1 UDGs (Ung) are the most efficient and ubiquitous proteins having an exquisite specificity for uracils in DNA. Ung are characterized by motifs A (GQDPY) and B (HPSPLS) sequences. We report a novel dimeric UDG, Blr0248 (...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chembazhi, Ullas Valiya, Patil, Vinod Vikas, Sah, Shivjee, Reeve, Wayne, Tiwari, Ravi P., Woo, Euijeon, Varshney, Umesh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449639/
https://ncbi.nlm.nih.gov/pubmed/28369586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx209
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