AUF1 facilitates microRNA-mediated gene silencing

Eukaryotic mRNA decay is tightly modulated by RNA-binding proteins (RBPs) and microRNAs (miRNAs). RBP AU-binding factor 1 (AUF1) has four isoforms resulting from alternative splicing and is critical for miRNA-mediated gene silencing with a distinct preference of target miRNAs. Previously, we have sh...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Min, Kyung-Won, Jo, Myung Hyun, Shin, Soochul, Davila, Sylvia, Zealy, Richard W., Kang, Soo Im, Lloyd, Lawson T., Hohng, Sungchul, Yoon, Je-Hyun
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449627/
https://ncbi.nlm.nih.gov/pubmed/28334781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx149
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