Llwytho...
New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival
Comparative modeling of the DNA-binding domain of human HSF1 facilitated the prediction of possible binding pockets for small molecules and definition of corresponding pharmacophores. In silico screening of a large library of lead-like compounds identified a set of compounds that satisfied the pharm...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nucleic Acids Res |
|---|---|
| Prif Awduron: | , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5449623/ https://ncbi.nlm.nih.gov/pubmed/28369544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx194 |
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