The dynamics of the monomeric restriction endonuclease BcnI during its interaction with DNA

Endonucleases that generate DNA double strand breaks often employ two independent subunits such that the active site from each subunit cuts either DNA strand. Restriction enzyme BcnI is a remarkable exception. It binds to the 5΄-CC/SGG-3΄ (where S = C or G, ‘/’ designates the cleavage position) targ...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Kostiuk, Georgij, Dikić, Jasmina, Schwarz, Friedrich W., Sasnauskas, Giedrius, Seidel, Ralf, Siksnys, Virginijus
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Nucleic Acid Enzymes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449598/
https://ncbi.nlm.nih.gov/pubmed/28453854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx294
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