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Dynamic chromatin accessibility modeled by Markov process of randomly-moving molecules in the 3D genome
Chromatin three-dimensional (3D) structure plays critical roles in gene expression regulation by influencing locus interactions and accessibility of chromatin regions. Here we propose a Markov process model to derive a chromosomal equilibrium distribution of randomly-moving molecules as a functional...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5449544/ https://ncbi.nlm.nih.gov/pubmed/28180283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx086 |
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