Mouse Genome-Wide Association Study of Preclinical Group II Pulmonary Hypertension Identifies Epidermal Growth Factor Receptor

Pulmonary hypertension (PH) is associated with features of obesity and metabolic syndrome that translate to the induction of PH by chronic high-fat diet (HFD) in some inbred mouse strains. We conducted a genome-wide association study (GWAS) to identify candidate genes associated with susceptibility...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Kelly, Neil J., Radder, Josiah E., Baust, Jeffrey J., Burton, Christine L., Lai, Yen-Chun, Potoka, Karin C., Agostini, Brittani A., Wood, John P., Bachman, Timothy N., Vanderpool, Rebecca R., Dandachi, Nadine, Leme, Adriana S., Gregory, Alyssa D., Morris, Alison, Mora, Ana L., Gladwin, Mark T., Shapiro, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449510/
https://ncbi.nlm.nih.gov/pubmed/28085498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0176OC
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