Mouse Genome-Wide Association Study of Preclinical Group II Pulmonary Hypertension Identifies Epidermal Growth Factor Receptor

Pulmonary hypertension (PH) is associated with features of obesity and metabolic syndrome that translate to the induction of PH by chronic high-fat diet (HFD) in some inbred mouse strains. We conducted a genome-wide association study (GWAS) to identify candidate genes associated with susceptibility...

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Bibliografske podrobnosti
izdano v:Am J Respir Cell Mol Biol
Main Authors: Kelly, Neil J., Radder, Josiah E., Baust, Jeffrey J., Burton, Christine L., Lai, Yen-Chun, Potoka, Karin C., Agostini, Brittani A., Wood, John P., Bachman, Timothy N., Vanderpool, Rebecca R., Dandachi, Nadine, Leme, Adriana S., Gregory, Alyssa D., Morris, Alison, Mora, Ana L., Gladwin, Mark T., Shapiro, Steven D.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2017
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449510/
https://ncbi.nlm.nih.gov/pubmed/28085498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0176OC
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