Anti-Double-Stranded DNA IgG Participates in Renal Fibrosis through Suppressing the Suppressor of Cytokine Signaling 1 Signals

Suppressor of cytokine signaling 1 (SOCS1) participates in renal fibrosis by downregulating Janus kinase 2 (JAK2)/signal transducer and activator of transcription 1 (STAT1)-mediated cytokine signaling. Recently, it was found that anti-double-stranded DNA (dsDNA) IgG induces the synthesis of profibro...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Wang, Ping, Yang, Jie, Tong, Fang, Duan, Zhaoyang, Liu, Xingyin, Xia, Linlin, Li, Ke, Xia, Yumin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449454/
https://ncbi.nlm.nih.gov/pubmed/28620377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00610
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