Serum Urate Levels Predict Joint Space Narrowing in Non-gout Patients with Medial Knee Osteoarthritis

OBJECTIVE: OA pathogenesis includes both mechanical and inflammatory features. Studies have implicated synovial fluid urate (UA) as a potential OA biomarker, possibly reflecting chondrocyte damage. Whether serum urate (sUA) levels reflect/contribute to OA is unknown. We investigated whether sUA pred...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Krasnokutsky, Svetlana, Oshinsky, Charles, Attur, Mukundan, Ma, Sisi, Zhou, Hua, Zheng, Fangfei, Chen, Meng, Patel, Jyoti, Samuels, Jonathan, Pike, Virginia C., Regatte, Ravinder, Bencardino, Jenny, Rybak, Leon, Abramson, Steven, Pillinger, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449226/
https://ncbi.nlm.nih.gov/pubmed/28217895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40069
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