Preferential utilization of conserved immunoglobulin heavy chain variable gene segments during human fetal life.

The ability to respond to specific antigens develops in a programmed fashion. Although the antibody repertoire in adults is presumably generated by stochastic combinatorial joining of rearranged heavy variable, diversity, and joining (VH-DH-JH) and light (VL-JL) chains, experimental evidence in the...

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Detalles Bibliográficos
Autores principales: Schroeder, H W, Wang, J Y
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC54489/
https://ncbi.nlm.nih.gov/pubmed/2117273
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