Low versus high dose of antimony for American cutaneous leishmaniasis: A randomized controlled blind non-inferiority trial in Rio de Janeiro, Brazil

BACKGROUND: Although high dose of antimony is the mainstay for treatment of American cutaneous leishmaniasis (ACL), ongoing major concerns remain over its toxicity. Whether or not low dose antimony regimens provide non-inferior effectiveness and lower toxicity has long been a question of dispute. ME...

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Pubblicato in:PLoS One
Autori principali: Saheki, Mauricio Naoto, Lyra, Marcelo Rosandiski, Bedoya-Pacheco, Sandro Javier, Antônio, Liliane de Fátima, Pimentel, Maria Inês Fernandes, Salgueiro, Mariza de Matos, Vasconcellos, Érica de Camargo Ferreira e, Passos, Sonia Regina Lambert, dos Santos, Ginelza Peres Lima, Ribeiro, Madelon Novato, Fagundes, Aline, Madeira, Maria de Fátima, Mouta-Confort, Eliame, Marzochi, Mauro Célio de Almeida, Valete-Rosalino, Cláudia Maria, Schubach, Armando de Oliveira
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448803/
https://ncbi.nlm.nih.gov/pubmed/28558061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178592
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