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The exceptionally high rate of spontaneous mutations in the polymerase delta proofreading exonuclease-deficient Saccharomyces cerevisiae strain starved for adenine

BACKGROUND: Mutagenesis induced in the yeast Saccharomyces cerevisiae by starvation for nutrilites is a well-documented phenomenon of an unknown mechanism. We have previously shown that the polymerase delta proofreading activity controls spontaneous mutagenesis in cells starved for histidine. To obt...

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主要な著者: Achilli, Alessandro, Matmati, Nabil, Casalone, Enrico, Morpurgo, Giorgio, Lucaccioni, Angela, Pavlov, Youri I, Babudri, Nora
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC544876/
https://ncbi.nlm.nih.gov/pubmed/15617571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-5-34
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