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Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes

Type 1 diabetes (T1D) is characterized by specific destruction of pancreatic insulin-producing beta cells accompanied by evidence of beta-cell-directed autoimmunity such as autoreactive T cells and islet autoantibodies (IAAs). Currently, T1D cannot be prevented or reversed in humans. T1D is easy to...

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Bibliografiske detaljer
Udgivet i:Immunotargets Ther
Main Authors: Itoh, Arata, Ridgway, William M
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448691/
https://ncbi.nlm.nih.gov/pubmed/28580341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/ITT.S117264
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