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Nuclear ERK5 inhibits progression of leukemic monocytes to macrophages by regulating the transcription factor PU.1 and heat shock protein HSP70

Differentiation therapy can supplement the therapy of APL, but other subtypes of AML are treated principally with cytotoxic agents, with few lasting remissions. While the induction of monocyte followed by macrophage differentiation by vitamin D derivatives (VDDs) is dramatic in cultured AML cells of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Leuk Lymphoma
Main Authors: Zheng, Ruifang, Studzinski, George P.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448461/
https://ncbi.nlm.nih.gov/pubmed/27748139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2016.1243675
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