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Shelterin components mediate genome reorganization in response to replication stress

The dynamic nature of genome organization impacts critical nuclear functions including the regulation of gene expression, replication, and DNA damage repair. Despite significant progress, the mechanisms responsible for reorganization of the genome in response to cellular stress, such as aberrant DNA...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Mizuguchi, Takeshi, Taneja, Nitika, Matsuda, Emiko, Belton, Jon-Matthew, FitzGerald, Peter, Dekker, Job, Grewal, Shiv I. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448194/
https://ncbi.nlm.nih.gov/pubmed/28490498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705527114
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