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Production of homogeneous glycoprotein with multisite modifications by an engineered N-glycosyltransferase mutant
Naturally occurring N-glycoproteins exhibit glycoform heterogeneity with respect to N-glycan sequon occupancy (macroheterogeneity) and glycan structure (microheterogeneity). However, access to well-defined glycoproteins is always important for both basic research and therapeutic purposes. As a resul...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5448120/ https://ncbi.nlm.nih.gov/pubmed/28381551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.777383 |
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