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The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2

Mitogen-activated protein kinase (MAPK) scaffold proteins, such as IQ motif containing GTPase activating protein 1 (IQGAP1), are promising targets for novel therapies against cancer and other diseases. Such approaches require accurate information about which domains on the scaffold protein bind to t...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Bardwell, A. Jane, Lagunes, Leonila, Zebarjedi, Ronak, Bardwell, Lee
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448102/
https://ncbi.nlm.nih.gov/pubmed/28396345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.767087
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