Gene and protein expression of a soluble form of CTLA-4 in a healthy dog

Cytotoxic T lymphocyte associated gene-4 (CTLA-4) is a costimulatory molecule, expressed on the surface of activated T cells that negatively regulates T cell activation. In humans, alternative splicing of the CTLA-4 gene generates two major isoforms of mRNA, and a soluble form of CTLA-4 (sCTLA-4) wa...

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Bibliografske podrobnosti
izdano v:J Vet Med Sci
Main Authors: TAGAWA, Michihito, YAMAMOTO, Yuhei, SHIMBO, Genya, IGUCHI, Aiko, XUAN, Xuenan, TOMIHARI, Mizuki, MIYAHARA, Kazuro
Format: Artigo
Jezik:Inglês
Izdano: The Japanese Society of Veterinary Science 2017
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447975/
https://ncbi.nlm.nih.gov/pubmed/28392507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.16-0583
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