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Reversing EGFR Mediated Immunoescape by Targeted Monoclonal Antibody Therapy

Uncontrolled growth is a signature of carcinogenesis, in part mediated by overexpression or overstimulation of growth factor receptors. The epidermal growth factor receptor (EGFR) mediates activation of multiple oncogenic signaling pathways and escape from recognition by the host immune system. We d...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Concha-Benavente, Fernando, Ferris, Robert L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447743/
https://ncbi.nlm.nih.gov/pubmed/28611673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00332
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