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Juxtaposition of expressed variable antigen genes with a conserved telomere in the bacterium Borrelia hermsii.

Borrelia hermsii, an agent of relapsing fever, survives in mammals through antigenic variation. Change in serotype-specific variable outer membrane proteins (Vmps) occurs when a Vmp gene at an expression site is replaced with a previously silent gene for another Vmp. Silent and active genes are on s...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kitten, T, Barbour, A G
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54475/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2385585/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.16.6077
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