Toll-Like Receptor 4 in Paraventricular Nucleus Mediates Visceral Hypersensitivity Induced by Maternal Separation

Neonatal maternal separation (MS) is a major early life stress that increases the risk of emotional disorders, visceral pain perception and other brain dysfunction. Elevation of toll-like receptor 4 (TLR4) signaling in the paraventricular nucleus (PVN) precipitates early life colorectal distension (...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Tang, Hui-Li, Zhang, Gongliang, Ji, Ning-Ning, Du, Lei, Chen, Bin-Bin, Hua, Rong, Zhang, Yong-Mei
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447361/
https://ncbi.nlm.nih.gov/pubmed/28611665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00309
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