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Exploration of the Conformational Dynamics of Major Histocompatibility Complex Molecules

Major histocompatibility complex (MHC) molecules are loaded with a wide variety of self- and non-self-peptides in their binding grooves and present these to T cell receptors (TCRs) in order to activate the adaptive immune system. A large number of crystal structures of different MHC alleles with dif...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yanaka, Saeko, Sugase, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446982/
https://ncbi.nlm.nih.gov/pubmed/28611781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00632
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