Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality

BACKGROUND: Investigation of basic chronic inflammatory mechanisms and development of new therapeutics targeting the respiratory tract requires appropriate testing systems, including those to monitor long- persistence. Human precision-cut lung slices (PCLS) have been demonstrated to mimic the human...

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Détails bibliographiques
Publié dans:J Occup Med Toxicol
Auteurs principaux: Neuhaus, Vanessa, Schaudien, Dirk, Golovina, Tatiana, Temann, Ulla-Angela, Thompson, Carolann, Lippmann, Torsten, Bersch, Claus, Pfennig, Olaf, Jonigk, Danny, Braubach, Peter, Fieguth, Hans-Gerd, Warnecke, Gregor, Yusibov, Vidadi, Sewald, Katherina, Braun, Armin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446749/
https://ncbi.nlm.nih.gov/pubmed/28559920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12995-017-0158-5
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