Inhibition of HIF-1α by PX-478 suppresses tumor growth of esophageal squamous cell cancer in vitro and in vivo

The aim of this study is to investigate the clinical significance of hypoxia inducible factor-1α (HIF-1α) expression in esophageal squamous cell cancer (ESCC) and clarify the effects of PX-478, a selective HIF-1α inhibitor, on ESCC both in vitro and in vivo. HIF-1α, cyclooxygenase-2 (COX-2) and prog...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Zhu, Yingming, Zang, Yuanwei, Zhao, Fen, Li, Zhenxiang, Zhang, Jianbo, Fang, Liang, Li, Minghuan, Xing, Ligang, Xu, Zhonghua, Yu, Jinming
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446484/
https://ncbi.nlm.nih.gov/pubmed/28560067
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