Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations

Hypertension is a leading cause of global disease, mortality, and disability. While individuals of African descent suffer a disproportionate burden of hypertension and its complications, they have been underrepresented in genetic studies. To identify novel susceptibility loci for blood pressure and...

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Argitaratua izan da:PLoS Genet
Egile Nagusiak: Liang, Jingjing, Le, Thu H., Edwards, Digna R. Velez, Tayo, Bamidele O., Gaulton, Kyle J., Smith, Jennifer A., Lu, Yingchang, Jensen, Richard A., Chen, Guanjie, Yanek, Lisa R., Schwander, Karen, Tajuddin, Salman M., Sofer, Tamar, Kim, Wonji, Kayima, James, McKenzie, Colin A., Fox, Ervin, Nalls, Michael A., Young, J. Hunter, Sun, Yan V., Lane, Jacqueline M., Cechova, Sylvia, Zhou, Jie, Tang, Hua, Fornage, Myriam, Musani, Solomon K., Wang, Heming, Lee, Juyoung, Adeyemo, Adebowale, Dreisbach, Albert W., Forrester, Terrence, Chu, Pei-Lun, Cappola, Anne, Evans, Michele K., Morrison, Alanna C., Martin, Lisa W., Wiggins, Kerri L., Hui, Qin, Zhao, Wei, Jackson, Rebecca D., Ware, Erin B., Faul, Jessica D., Reiner, Alex P., Bray, Michael, Denny, Joshua C., Mosley, Thomas H., Palmas, Walter, Guo, Xiuqing, Papanicolaou, George J., Penman, Alan D., Polak, Joseph F., Rice, Kenneth, Taylor, Ken D., Boerwinkle, Eric, Bottinger, Erwin P., Liu, Kiang, Risch, Neil, Hunt, Steven C., Kooperberg, Charles, Zonderman, Alan B., Laurie, Cathy C., Becker, Diane M., Cai, Jianwen, Loos, Ruth J. F., Psaty, Bruce M., Weir, David R., Kardia, Sharon L. R., Arnett, Donna K., Won, Sungho, Edwards, Todd L., Redline, Susan, Cooper, Richard S., Rao, D. C., Rotter, Jerome I., Rotimi, Charles, Levy, Daniel, Chakravarti, Aravinda, Zhu, Xiaofeng, Franceschini, Nora
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446189/
https://ncbi.nlm.nih.gov/pubmed/28498854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006728
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