Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations

Hypertension is a leading cause of global disease, mortality, and disability. While individuals of African descent suffer a disproportionate burden of hypertension and its complications, they have been underrepresented in genetic studies. To identify novel susceptibility loci for blood pressure and...

Full description

Saved in:
Bibliographic Details
Published in:PLoS Genet
Main Authors: Liang, Jingjing, Le, Thu H., Edwards, Digna R. Velez, Tayo, Bamidele O., Gaulton, Kyle J., Smith, Jennifer A., Lu, Yingchang, Jensen, Richard A., Chen, Guanjie, Yanek, Lisa R., Schwander, Karen, Tajuddin, Salman M., Sofer, Tamar, Kim, Wonji, Kayima, James, McKenzie, Colin A., Fox, Ervin, Nalls, Michael A., Young, J. Hunter, Sun, Yan V., Lane, Jacqueline M., Cechova, Sylvia, Zhou, Jie, Tang, Hua, Fornage, Myriam, Musani, Solomon K., Wang, Heming, Lee, Juyoung, Adeyemo, Adebowale, Dreisbach, Albert W., Forrester, Terrence, Chu, Pei-Lun, Cappola, Anne, Evans, Michele K., Morrison, Alanna C., Martin, Lisa W., Wiggins, Kerri L., Hui, Qin, Zhao, Wei, Jackson, Rebecca D., Ware, Erin B., Faul, Jessica D., Reiner, Alex P., Bray, Michael, Denny, Joshua C., Mosley, Thomas H., Palmas, Walter, Guo, Xiuqing, Papanicolaou, George J., Penman, Alan D., Polak, Joseph F., Rice, Kenneth, Taylor, Ken D., Boerwinkle, Eric, Bottinger, Erwin P., Liu, Kiang, Risch, Neil, Hunt, Steven C., Kooperberg, Charles, Zonderman, Alan B., Laurie, Cathy C., Becker, Diane M., Cai, Jianwen, Loos, Ruth J. F., Psaty, Bruce M., Weir, David R., Kardia, Sharon L. R., Arnett, Donna K., Won, Sungho, Edwards, Todd L., Redline, Susan, Cooper, Richard S., Rao, D. C., Rotter, Jerome I., Rotimi, Charles, Levy, Daniel, Chakravarti, Aravinda, Zhu, Xiaofeng, Franceschini, Nora
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446189/
https://ncbi.nlm.nih.gov/pubmed/28498854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006728
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items