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CCL20 secreted from IgA1-stimulated human mesangial cells recruits inflammatory Th17 cells in IgA nephropathy

IgA nephropathy (IgAN) is the most common primary glomerulonephritis characterized by human mesangial cells (HMC) proliferation and extracellular matrix expansion associated with immune deposits consisting of galactose-deficient IgA1. However, how IgA1 contributes to IgAN has yet to be completely el...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lu, Guoyuan, Zhang, Xiaopan, Shen, Lei, Qiao, Qing, Li, Yuan, Sun, Jieqiong, Zhang, Jinping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446182/
https://ncbi.nlm.nih.gov/pubmed/28552941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178352
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