Sex-specific effect of CPB2 Ala147Thr but not Thr325Ile variants on the risk of venous thrombosis: A comprehensive meta-analysis

BACKGROUND: Thrombin activatable fibrinolysis inhibitor (TAFI), encoded by the Carboxypeptidase B2 gene (CPB2), is an inhibitor of fibrinolysis and plays a role in the pathogenesis of venous thrombosis. Experimental findings support a functional role of genetic variants in CPB2, while epidemiologica...

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Foilsithe in:PLoS One
Main Authors: Zwingerman, Nora, Medina-Rivera, Alejandra, Kassam, Irfahan, Wilson, Michael D., Morange, Pierre-Emmanuel, Trégouët, David-Alexandre, Gagnon, France
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446132/
https://ncbi.nlm.nih.gov/pubmed/28552956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177768
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