NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis

Smooth muscle cell (SMC) proliferation and fibrosis contribute to the development of advanced atherosclerotic lesions. Oxidative stress caused by increased production or unphysiological location of reactive oxygen species (ROS) is a known major pathomechanism. However, in atherosclerosis, in particu...

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Détails bibliographiques
Publié dans:Free Radic Biol Med
Auteurs principaux: Di Marco, Elyse, Gray, Stephen P., Kennedy, Kit, Szyndralewiez, Cedric, Lyle, Alicia N., Lassègue, Bernard, Griendling, Kathy K., Cooper, Mark E., Schmidt, Harald H.H.W., Jandeleit-Dahm, Karin A.M.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446082/
https://ncbi.nlm.nih.gov/pubmed/27445103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.07.013
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