Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes

BACKGROUND: Evolutionarily conserved sequences within or adjoining orthologous genes often serve as critical cis-regulatory regions. Recent studies have identified long, non-coding genomic regions that are perfectly conserved between human and mouse, termed ultra-conserved regions (UCRs). Here, we f...

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Veröffentlicht in:	BMC Genomics
Hauptverfasser:	Sandelin, Albin, Bailey, Peter, Bruce, Sara, Engström, Pär G, Klos, Joanna M, Wasserman, Wyeth W, Ericson, Johan, Lenhard, Boris
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2004
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15613238/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2164-5-99
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