Establishment of a rat model of thrombosis induced by intravenous injection of anti-phosphatidylserine–prothrombin complex antibody

Objective. Recent studies have suggested that aPS-PT antibody is one of the most relevant autoantibodies to APS. This study aimed to demonstrate the pathogenicity of aPS-PT antibody in vivo. Methods. At first, cultured rat vascular endothelial cells (RECs) were exposed to calf thymus-derived histone...

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Vydáno v:Rheumatology (Oxford)
Hlavní autoři: Yamada, Mai, Kawakami, Tamihiro, Takashima, Kohei, Nishioka, Yusuke, Nishibata, Yuka, Masuda, Sakiko, Yoshida, Shigeru, Tomaru, Utano, Ishizu, Akihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Basic and Translational Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445602/
https://ncbi.nlm.nih.gov/pubmed/28073955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kew477
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