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Heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is an immune complication of heparin therapy caused by antibodies to complexes of platelet factor 4 (PF4) and heparin. Pathogenic antibodies to PF4/heparin bind and activate cellular FcγRIIA on platelets and monocytes to propagate a hypercoagulable state culmin...

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書目詳細資料
發表在:Blood
主要作者: Arepally, Gowthami M.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445568/
https://ncbi.nlm.nih.gov/pubmed/28416511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-709873
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