The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells

BACKGROUND: Malignant pleural mesothelioma is an aggressive cancer, characterized by rapid progression and high mortality. Persistence of tumor-initiating cells (TICs, or cancer stem cells) after cytotoxic drug treatment is responsible for tumor relapse, and represents one of the main reasons for th...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Pattarozzi, Alessandra, Carra, Elisa, Favoni, Roberto E., Würth, Roberto, Marubbi, Daniela, Filiberti, Rosa Angela, Mutti, Luciano, Florio, Tullio, Barbieri, Federica, Daga, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445511/
https://ncbi.nlm.nih.gov/pubmed/28545562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0573-7
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