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The complex domain architecture of SAMD9 family proteins, predicted STAND-like NTPases, suggests new links to inflammation and apoptosis

ABSTRACT: We report a comprehensive computational dissection of the domain architecture of the SAMD9 family proteins that are involved in antivirus and antitumor response in humans. We show that the SAMD9 protein family is represented in most animals and also, unexpectedly, in bacteria, in particula...

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Detalhes bibliográficos
Publicado no:Biol Direct
Main Authors: Mekhedov, Sergei L., Makarova, Kira S., Koonin, Eugene V.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445408/
https://ncbi.nlm.nih.gov/pubmed/28545555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-017-0185-2
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