The combination of nano-calcium sulfate/platelet rich plasma gel scaffold with BMP2 gene-modified mesenchymal stem cells promotes bone regeneration in rat critical-sized calvarial defects

BACKGROUND: Mesenchymal stem cells (MSCs) can be differentiated into an osteoblastic lineage in the presence of growth factors (GFs). Platelet-rich plasma (PRP), which can be easily isolated from whole blood, contains a large amount of GFs, and, therefore, promotes bone growth and regeneration. The...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Liu, Zunpeng, Yuan, Xue, Fernandes, Gabriela, Dziak, Rosemary, Ionita, Ciprian N., Li, Chunyi, Wang, Changdong, Yang, Shuying
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445399/
https://ncbi.nlm.nih.gov/pubmed/28545565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0574-6
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