Increased serum level of soluble interleukin-2 receptor is associated with a worse response of metastatic clear cell renal cell carcinoma to interferon alpha and sequential VEGF-targeting therapy

BACKGROUND: Renal cell carcinoma (RCC) is a tumor with immunogenic properties. Soluble interleukin-2 receptor (sIL-2R) has a role in T cell activation and may be important for immune regulation in various conditions, including infections, transplantation rejection, autoimmune inflammatory states, an...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Nukui, Akinori, Masuda, Akinori, Abe, Hideyuki, Arai, Kyoko, Yoshida, Ken-Ichiro, Kamai, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445282/
https://ncbi.nlm.nih.gov/pubmed/28545581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3369-3
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