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Intratumoral FoxP3(+)Helios(+) Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer

Regulatory T cells (Tregs) can be antitumorigenic or pro-tumorigenic in colorectal cancer (CRC) depending on the presence of different Treg subsets with various immunosuppressive molecules. Some studies reported the phenotypic characteristics of tumor-infiltrating immune cells in CRC, but limited st...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Syed Khaja, Azharuddin Sajid, Toor, Salman M., El Salhat, Haytham, Ali, Bassam R., Elkord, Eyad
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445103/
https://ncbi.nlm.nih.gov/pubmed/28603527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00619
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