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Immune checkpoint inhibitors in challenging populations

Immune checkpoint inhibitors, including those targeting the PD-1/PD-L1 and CTLA-4 pathways, are revolutionizing cancer therapeutics. Both activity and toxicities largely stem from unleashing tumor- or host-specific cytotoxic T cells. Many patients seen in routine clinical practice did not qualify fo...

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Podrobná bibliografie
Vydáno v:Cancer
Hlavní autoři: Johnson, Douglas B., Sullivan, Ryan J., Menzies, Alexander M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445005/
https://ncbi.nlm.nih.gov/pubmed/28241095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30642
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