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Determination of sites of U50,488H-promoted phosphorylation of the mouse kappa opioid receptor (KOPR): Disconnect between KOPR phosphorylation and internalization

Phosphorylation sites of KOPR following treatment with the selective agonist U50,488H were identified after affinity purification, SDS-PAGE, in-gel digestion with Glu-C and LC-MS/MS. Single- and double-phosphorylated peptides were identified containing phosphorylated S356, T357, T363 and S369 in the...

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Detalles Bibliográficos
Publicado en:Biochem J
Main Authors: Chen, Chongguang, Chiu, Yi-Ting, Wu, Wenman, Huang, Peng, Mann, Anika, Schulz, Stefan, Liu-Chen, Lee-Yuan
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444940/
https://ncbi.nlm.nih.gov/pubmed/26635353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141471
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