Synergistic antidepressant-like effects between a kappa opioid antagonist (LY2444296) and a delta opioid agonist (ADL5859) in the mouse forced swim test

Kappa opioid (KOP) receptor antagonists and delta opioid (DOP) receptor agonists have antidepressant-like effects in animal tests and may be useful for treatment-resistant depression in humans. In this study, we examined whether the combination of a KOP receptor antagonist and a DOP receptor agonist...

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Vydáno v:Eur J Pharmacol
Hlavní autoři: Huang, Peng, Tunis, Julia, Parry, Christopher, Tallarida, Ronald, Liu-Chen, Lee-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444937/
https://ncbi.nlm.nih.gov/pubmed/27044434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.03.061
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