The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription

The type I interferon (IFN) response is imperative for the establishment of the early antiviral immune response. Here we report the identification of the first type I IFN antagonist encoded by murine cytomegalovirus (MCMV) that shuts down signaling following pattern recognition receptor (PRR) sensin...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Chan, Baca, Gonçalves Magalhães, Vladimir, Lemmermann, Niels A. W., Juranić Lisnić, Vanda, Stempel, Markus, Bussey, Kendra A., Reimer, Elisa, Podlech, Jürgen, Lienenklaus, Stefan, Reddehase, Matthias J., Jonjić, Stipan, Brinkmann, Melanie M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444856/
https://ncbi.nlm.nih.gov/pubmed/28542326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006382
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